Of 5876 men, 4.7% (N = 275) reported an incident nonspine fracture during follow-up (11.46/1000 person-years). Proportional hazards models were used to develop multivariable models, selecting variables and controlling for BMD. Triannual mailed questionnaires ascertained incident fracture reported fractures were adjudicated by physicians using medical records and X-ray reports. Baseline assessments of demographic, lifestyle, medical history, functional status, anthropometry, and cognitive, visual, and neuromuscular function were assessed by questionnaire or examination. We examined the associations between a comprehensive set of clinical risk factors and risk of nonspine fracture in older men and whether determinants of fracture risk were independent of total hip BMD.Ī total of 5995 men > or =65 years of age were recruited from six communities in the Unites States and followed prospectively for an average of 4.1 years. There are few prospective studies of fracture determinants in men. Six clinical risk factors predicted fracture risk independent of hip BMD: tricyclic antidepressant use, previous fracture, inability to complete a narrow walk trial, falls in previous year, age > or =80 years, and depressed mood. communities followed an average of 4.1 years. We examined determinants of nonvertebral fracture in elderly men from six U.S.
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